Come to find out Akita blood platelets can explode in storage causing hi readings. There is NO other explanation for this rapid decline and the only change has been THIS drug. No more of this med! Mine is due for another dose next week and I don't know what to do. The vet came and picked her up and cut her opened and said and told me she could anything wrong with her so it was either she was poisoned or it was a neurological disorder. Find the Right Simparica for your dog. Hoping for good news with your pup!! I only researched it after he started not feeling well, just trusted my vet that this was safe. Product Information: Simparica Trio (sarolaner, moxidectin, and pyrantel) Chewables are a safe monthly chewable for dogs that prevents heartworm disease, kills adult fleas and is indicated for the treatment and prevention flea infestations, the treatment and control of tick infestations, and the treatment and control of roundworms and . He also had a seizure that lasted for about 2 minutes in the middle of the night about 2 months ago and it was the most horrifying thing to watch and feel so helpless. I could never forgive myself. She wanted me to monitor him carefully and wait to see how he did on his next dose of Simparica before continuing to prescribe it. Our Pickles died last year after just 3 doses, and our vet basically said we were crazy. Bella is a very anxious dog and is my husbands shadow. The cardiologist found no heart condition that would cause this. well my lola went into labor xmas day. So from what I understand, your dog was on this for 6 months and got the serious symptoms after that? He's been in an emergency hospital for two nights, no signs of improvement despite blood transfusions and other symptoms. I have a vet appointment tomorrow to figure it out. My vet is aware of this and prescribed simparica. Im at the 30 day mark from giving him the symparico and he no longer has pain but they want to continue him on a 4-6 months treatment of steroids as if its meningitis but I dont love the idea because the steroids have side effects too. 300+ Cute Cat Names for Every Kind of Kitty. Simparica may cause neurologic signs such as tremors, unsteadiness and/or seizures in dogs with or without a history of neurologic disorders. My vet never mentioned that puppies under 6months cannot be prescribed this medication. Use with caution in dogs with a history of seizures or neurologic disorders. Refused to eat the rice and sweet potato I made for him last night. Never any issues with bravecto so we'll return to that medication. They have become so bad that she cries and whimpers any time she is laying down. He already has canine dementia on and off. Our dog has had 2 Seizures this month and we are going to stop using Simparica. the vet suggested it because she has hookworm..This morning she was shaking and no appetite..After reading all these comments I am scared to death for her. Not drinking any water but drooling and swallowing all the time. When did you stop giving the Simparico Trio? Bentlee trusts me an I let him down on this one. Pet Bucket Ltd is a UK registered company|Company no: 08345021|BTC Bessemer Drive Stevenage, SG1 2DX UK. Her heartbeat was more of a vibration than a beat and the vet wanted her to see a cardiologist. Topical only for me from now on. Are there any side effects to Simparica Trio? This month 5/1 gave him another dose and here we are 12 days later with diarrhea and no appetite. I just started my 80 pound pit on this same medication yesterday. If you need to get rid of parasites, spot-on (the one by a German company is effective enough) will do the job and do it safely. Simparica, Nexgard, Bravecto and Credelio are part of a group called Isoxazoline drugs. So I started searching and came across this blog and my heart just sank. After her first dose she had diarrhea, vomiting and developed a terrible wheezing hacking cough. Simparica and Simparica Trio are available by prescription only. We go for more bloodwork today and are praying for better news. Naturally, I want to make sure that she never has to go through that again. In a weak moment last week she prescribed Simparica for a flea problem my 5 year old Springer was having. I would say these changes may have happened more suddenly than just normal aging so I'm not going to give him this medication anymore. How common are Simparica side effects? He cant handle those unexpected noises. The very next day he had diarrhea, and had it for 6 days. But unfortunately it's only a dog is the big Pharma tune. We live in Texas and I have only used an isoxazoline preventative when insect populations get out of control in my area, like they are now. Vet said "cant be Simparica because he had 9 days ago". Vet thinks it may be Addision disease and wants to test for it. The flea components vary but having had one seizure you're now prone to being sensitive to even the "safer" ones. Did your dog pass away? Head down, facing the wall, tremors, lethargic, and she can't seem to see well. What do I do? My one year old has severe diarrhea and is very agitated and anxious. Since the weather was turning cold, I stopped giving her the Simparica until spring. We took him to the animal er and they checked his vitals and he was fine. I dont want to have to put my dog down but hes suffering. The company's thinking must be the profits outweigh the loses from any lawsuits lost its important to note that the law treats animals as property and the fix value of a dog is quite small and limited. Seizures continue and its Monday. This past October he just wasn't the same. I did some research and because he seemed otherwise fine, I assumed it was "small white dog" shaking due to his breed mix. Lethargy: Some dogs may become temporarily lethargic or drowsy after taking Simparica Trio. Will NEVER give this to my dog again. In a well-controlled laboratory study, SIMPARICA TRIO began to kill fleas at 4 hours and demonstrated 100% effectiveness at 8 hours after initial administration. Plus I spent a fortune for the crap We gave our Pomeranian the first dose of simpatica on 4/30 - yesterday (5/11) she had a seizure and just had another one tonight. The leaflet inside at least needs to be changed to have the correct information on it. DO NOT give this poison to your pets. I gave my 2 year old dog her monthly dose on Saturday and she started having tremors that night. We have a 3 month old Aussie labradoodle and the breeder warned against oral flea meds. Just be aware that no oral tick medicine is safe, all are from the same class of drugs. 2-6 days in vomiting here and there. Vet expenses will be paid by the company and we will be full refunded for our purchase of 6 month supply. Her Liver enzymes were also through the roof. I gave my 10 year old Bull Terrier a dose of Simparico Trio Thursday December 3. He's a 1 1/2 y.o. My vet recommended the tablet to save on monthly costs for flea and tick treatment. My Irish setter is weak on her left side, left side of her face is drooping and she now carries her head with a tilt to the left. So bad that the FDA made them put a huge warning now on the package. If it was due to the Simparica, then it would expected to be resolved within a day or two. Please anyone let me know if there is a class action law suit or where we can start one? Very "out of it". Gave my 28lb German Spitz her monthly prescibed dose of Simparica. He has become more aggressive and has been growling at me sometimes when I try to move him. Any advice on the diarrhea? I advise all pet owners to know the side effects. Now tremors started. Today shes been panting. Has started to stumble and sleeps 10 to 12 hours at a time. Simparica TRIO also works for the control and treatment of adult hookworm and adult roundworms. Note: Lotilaner (Credelio) AE reports were not available via FOIA due to the newness of this drug Spinosad (Comfortis) AE reports not available at time of analysis Simparicaworks by impacting the nervous system of invertebrates such as fleas and ticks. He has been getting groomed since he was 3 months old but we've noticed that he has been getting more anxious with time. Simparica Trio (Sarolaner, moxidectin, and pyrantel chewable tablets) prevents heartworm disease caused by Dirofilaria immitis . corgi lying in grass next to woman's feet. Two months no flare up no more scabs and loosing hair. He was very anxious when I left him and picked him up. He took simparica trio 3 weeks ago and I cant wait until its out of his system! I sure hope we don't have ongoing problems. Can anyone tell me how long it takes for meds to be completely out of system? I am so worried about her I called to explain and was told to feed her chicken and rice and if she isn't improved take her to Emergency Vet Hospital. Im trying to understand how. I brought him to the vet and they keep trying to say excessive water drinking isnt a side effect but its the only thing that is different that Ive given my pup. She is more worried about excessive thirst, lip smacking and her kidneys. Simparica Trio is the brand name of a chewable tablet that protects dogs from heartworm disease, fleas, five species of ticks, and two types of intestinal parasites. Ekko then started having seizures in May,June and July. My 9 month old puppy started acting very lethargic after taking simparica trio. If you accidentally ingest a pet medication, call your physician or the national Poison Control Center hotline at 800-222-1222. Did you do this yourself or let the vet? Really? Get practical pet health tips, articles, and insights from our veterinary community delivered weekly to your inbox. I want to thank everyone who posted I could not find enough information on other sites. I am terrified--wish I would of seen this sooner. This is terrible. There was no clear diagnosis but it was clearly neurological. And he was on Comfortis before and did fine. Called vet and was advised chicken and rice by tech - vet did not come to the phone even tho I asked to speak to her twice. She had right sided weakness, with right sided neglect( the inability to process stimuli with impaired spatial recognition ). There is a possibility it isn't the cause, but it is the only reason I can find and it aligns with the stories of others. I wouldnt have given it to her. 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